Huntzinger E, Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat Rev Genet. 2011 Feb;12(2):99-110. Review.
Silencing RNAs: organisers and coordinators of complexity in eukaryotic organisms
Posts Tagged ‘Izaurralde E’
Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.
Huntzinger E, Braun JE, Heimstädt S, Zekri L, Izaurralde E. Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO J. 2010 Dec 15;29(24):4146-60. Epub 2010 Nov 9.
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.
Kashima I, Jonas S, Jayachandran U, Buchwald G, Conti E, Lupas AN, Izaurralde E. SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. Genes Dev. 2010 Oct 7. [Epub ahead of print]
HPat provides a link between deadenylation and decapping in metazoa.
Haas G, Braun JE, Igreja C, Tritschler F, Nishihara T, Izaurralde E. HPat provides a link between deadenylation and decapping in metazoa. J Cell Biol. 2010 Apr 19;189(2):289-302.
The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa.
Braun JE, Tritschler F, Haas G, Igreja C, Truffault V, Weichenrieder O, Izaurralde E. The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa. EMBO J. 2010 Jul 21;29(14):2368-80. Epub 2010 Jun 11.
Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein.
Boland A, Tritschler F, Heimstädt S, Izaurralde E, Weichenrieder O. Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein. EMBO Rep. 2010 Jul;11(7):522-7. Epub 2010 Jun 11.
Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu.
Tritschler F, Huntzinger E, Izaurralde E. Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu. Nat Rev Mol Cell Biol. 2010 Apr 9. [Epub ahead of print]
The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing.
Eulalio A, Tritschler F, Izaurralde E. The GW182 protein family in animal cells: new insights into domains required for miRNA-mediated gene silencing. RNA. 2009 Aug;15(8):1433-42. Epub 2009 Jun 17. Review.
A C-terminal silencing domain in GW182 is essential for miRNA function.
Eulalio A, Helms S, Fritzsch C, Fauser M, Izaurralde E. A C-terminal silencing domain in GW182 is essential for miRNA function.RNA. 2009 Apr 21. [Epub ahead of print]
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.
Lazzaretti D, Tournier I, Izaurralde E. The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins. RNA. 2009 Apr 21. [Epub ahead of print]