Posts Tagged ‘Enright AJ’

Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets.

Palmer RD, Murray MJ, Saini HK, van Dongen S, Abreu-Goodger C, Muralidhar B, Pett MR, Thornton CM, Nicholson JC, Enright AJ, Coleman N; Children’s Cancer and Leukaemia Group. Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets. Cancer Res. 2010 Apr 1;70(7):2911-23. Epub 2010 Mar 23.


MapMi: automated mapping of microRNA loci.

Guerra-Assunção JA, Enright AJ MapMi: automated mapping of microRNA loci. BMC Bioinformatics. 2010 Mar 16;11:133.

MapMi is a tool designed to locate miRNA precursor sequences in existing genomic sequences (e.g Ensembl and Ensembl Metazoa), using potential mature miRNA sequences as input.

After searching the genome for the provided mature sequences, these hits are extended and classified taking into account major structural properties of known miRNA precursors.

MapMi uses Bowtie and RNAfold third-party tools. Please check their websites for more details.
For more informations about the methods behind MapMi, please check the references section