baySeq is a package for calculating Differential Expression in Solexa-type, or count, data for the R Project For Statistical Computing. It was previously available on these pages but is now part of Bioconductor. For more information please see the Bioconductor website.
For details on the methods being used, consult Hardcastle et al. (2009) Empirical Bayesian methods for estimating differential expression in count data.
SIROCCO Coordinator David Baulcombe receives knighthood for services to plant sciences. Read more here
SIROCCO Partner Detlef Weigel elected to US National Academy of Sciences as a Full Member
The SIROCCO website has moved from its plantsci.cam.ac.uk address to its rightful home at http://www.sirocco-project.eu/. Please update your bookmarks!
RNAi News has written a review of the Sirocco Bioinformatics site.
There is a guide added to the Bioinformatics Tools sub-site helping newbies take first steps in using the tools and provided by the site. Click here to get the guide.
The SIROCCO website has recieved a fresh look for a fresh year. Improvements include the new, simpler layout and the addition of the Bioinformatics data and tools subsite. There are also changes made to the News and Publication pages amongst other things. Enjoy!
SIROCCO was represented at the RNAi Europe meeting in Barcelona 19th-21st September 2007.
Partner Eric Miska gave a talk on 19th September entitled microRNAs in Animal Development and Human Cancer.
Aileen Hogan presented a poster highlighting the SIROCCO competitive call. Xavier Estivill and his lab members Mónica Báñez, Eulalia Marti, Josep Mercader, Elena Minones-Moyano, Margarita Muiños and Ester Saus presented their experiments showing miRNA expression changes in neurodegenerative processes and also in the hypothalamus of an anorexia mouse model. Exiqon presented results of microRNA expression profiling using LNA technology.
This years meeting will be held in Cambridge, UK. Click for the Sirocco 2008 AGM Agenda
David Baulcombe, SIROCCO Coordinator, is being honoured with the 2008 Lasker Award for Basic Medical Research for his discovery of how tiny RNA molecules govern gene activity through RNA silencing. David established that small RNAs silence genes in plants, thus catalyzing discoveries of many such RNAs in a wide range of living things. His findings led to the identification of the biochemical machinery that unifies numerous processes by which small RNAs govern gene activity
First presented in 1946, the Lasker Awards are America’s most distinguished honor for outstanding basic and clinical medical research discoveries and for lifetime contributions to medical science. David Baulcombe and co-recipients Victor Ambros and Gary Ruvkun will be presented with the awards at a ceremony on Friday, September 26th at the Pierre Hotel in New York City.