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Silencing RNAs: organisers and coordinators of complexity in eukaryotic organisms

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« Identification of novel cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo.
Semiconserved regulation of mesendoderm differentiation by microRNAs. »

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.

Bramsen JB, Laursen MB, Nielsen AF, Hansen TB, Bus C, Langkjær N, Babu BR, Højland T, Abramov M, Van Aerschot A, Odadzic D, Smicius R, Haas J, Andree C, Barman J, Wenska M, Srivastava P, Zhou C, Honcharenko D, Hess S, Müller E, Bobkov GV, Mikhailov SN, Fava E, Meyer TF, Chattopadhyaya J, Zerial M, Engels JW, Herdewijn P, Wengel J, Kjems J. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity.Nucleic Acids Res. 2009 Mar 12. [Epub ahead of print]

Tags: Joint Publication, Kjems J, Meyer TF

Filed under Publications.

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